《血站合格血液储存库射频识别(RFID)技术应用规范》地方标准编制研究

血液储存精细化管理是血液质量与安全的保障。苏州市中心血站编制了《血站合格血液储存库射频识别(RFID)技术应用规范》地方标准,规范了血站合格血液储存库射频识别(RFID)技术应用过程中的应用模型、RFID电子标签的要求、RFID读写设备的要求、信息系统的功能要求、典型应用场景以及异常情况预防与处理等内容,保障临床用血安全,促进无偿献血事业高质量发展。     

互联网云平台影像存储与传输系统在区域医疗中的应用

以延安大学附属医院为例,在介绍其影像存储与传输系统（Picture Archiving and Communication System,PACS）发展历程及存在问题的基础上,提出构建基于互联网云平台的PACS,阐述系统的体系架构和具体实现方式并给出其应用效果。     

Detection of radiographic findings in lung fibrosis using storage phosphor plates

The aim of this work was to examine the influence of the filter kernel size on the detectability of differing radiological findings in interstitial lung disease. In 97 patients with confirmed pulmonary fibrosis chest radiographs were obtained with a film-screen system of speed class 200 and with correspondingly exposed storage phosphorous plates. The size of the filter kernel used for the image postprocessing varied between sigma 5 and sigma 70. The detectability of interstitial lung changes was evaluated independently by eight readers on the basis of a defined rating system. The results were analysed using multifactorial analysis of variance with Scheffé test at a significance level of p = 0.05. Small kernel sizes (S 5, S 10) combined with high edge enhancement were only of benefit in the imaging of septal lines, but reduced the detectability of nodular and reticular structures. Good detail detectability of both micronodules and septal lines was obtained with a medium kernel size of sigma 40. Storage phosphor radiography utilizing the appropriate choice of postprocessing parameters provides equivalent image quality for evaluating interstitial lung changes compared with a modern film-screen technique. Received 22 January 1996; Revision received 29 April 1996; Accepted 22 August 1996     

Accumulation of smooth cisterns,multivesicular bodies and “zebra” bodies in neurons

Summary The ultrastructural and biochemical study of cerebral and liver biopsies from a two-year-old boy with 20 month history of psychomotor retardation, hypotonia and hyporeflexia is presented. Although the case cannot be considered, at the present time, as a separate entity in view of the failure of the biochemical studies of identifying the stored material, the ultrastructural features, which include clustered agranular cisterns of endoplasmic reticulum and numerous multivesicular bodies and zebra bodies in neurons, indicate a storage disorder morphologically different from those reported to date. In the present case, morphological and cytochemical findings suggest that the agranular endoplasmic reticulum may give trise to multivesicular bodies which, in turn, may become dense bodies and zebra bodies.Supported by U.S.P.H.S. Grants NS 05572-06, NS 08933-01, NS 08420-02, NIN FR 75, by the Inex J. Warriner Memorial Grant for Research in Multiple Sclerosis (670-A-1) from the National Multiple Sclerosis Society.     

Isolated chromaffin granules maintenance of ATP content during incubation at 31 degrees C

Chromaffin granules incubated at 31°C, lose 30% of their catecholamines and nucleotides in 4 hr. However, in the presence of ATP and Mg²⁺ less than 10% of the catecholamines and nucleotides are released. Apparently the ATP-stimulated uptake of catecholamines prevents both the loss of catecholamines and that of nucleotides.     

Effect of lidoflazine (R 7904) on uptake and release of serotonin by human platelets in vitro

Summary At low concentrations in vitro (starting at 5×10^–8 M), lidoflazine reduces the velocity of serotonin uptake by human platelets suspended in Tyrodealbumin. Inhibition is of a non-competitive type and is not enhanced by prolonged compound incubation.At higher concentrations (starting at 1.6×10^–6 M) lidoflazine causes release of radioactive serotonin from platelets. The extent of release is dependent on concentration, duration of incubation and temperature and is not reduced by calcium chelation or papaverine pre-treatment. Similar but less pronounced effects on uptake and release reactions occur with dipyridamole. The possible mode of action of lidoflazine on platelet storage of serotonin is discussed.     

The nature of storage deficits and state-dependent retrieval under marihuana

To explore the nature of the storage deficit produced by marihuana intoxication and to determine if retrieval is state dependent for this drug, 48 subjects were presented 10–20-word lists before receiving an oral dose of marihuana and another 10 lists following drug administration. Subjects studied half of each set of 10 pre-drug and 10 post-drug lists using an overt fixed-rehearsal procedure and half using their normal covert free-rehearsal procedure. On Day 1 of the experiment an immediate-recall test followed each of the 20 lists presented. The marihuana-induced deficit in immediate-recall performance on Day 1 for free-rehearsal lists was not eliminated when the fixed-rehearsal procedure was used. Thus, marihuana intoxication impaired the storage of information even when overt rehearsal in the drug and no-drug states was equated. Three days later (Day 4) subjects returned, half receiving marihuana (Drug Group) and half receiving placebo (Placebo Group). All subjects were then administered delayed recall, recognition, and order tests on the words presented on Day 1. Delayed recall performance was asymmetrically state dependent, whereas delayed recognition performance was not state dependent.This research was supported by the van Ameringen Foundation and National Institutes of Mental Health grant 21747.The authors thank Caroline Bowker, Claire Darley, Glenn Huntsherger, Saul Kantor, Frances Moore, Patricia Murphy, Peggy Murphy, and Margaret Rosen-bloom for their technical assistance.     

Functional deficits in phonological working memory in children with intellectual disabilities

Recent studies indicate that children with intellectual disabilities have functional limitations primarily in the phonological loop of working memory (Baddeley, 1986). These findings are indicative of a specific structural deficit. Building on this research, the present study examines whether it is possible to identify specific phonological subfunctions as causal factors in these qualitative deviations from typical development found in children with intellectual disabilities. In a three-group design, specific subfunctions of phonological working memory were examined in students of the same mental age (one group of 15-year-olds with mild intellectual disability [IQ 50-69], one group of 10-year-olds with borderline intellectual disability [IQ 70-84], and one group of 7-year-olds of average intelligence [IQ 85-115]). The automatic activation of the subvocal rehearsal process was operationalized by the word-length effect; the size of the phonological store, by a task involving repetition of nonwords of differing syllable length; and accuracy of processing, by both the phonological similarity effect and the quality of acoustic presentation of the nonword repetition task (distorted vs. undistorted item presentation). The results revealed impairment of the phonological store only in terms of reduced storage capacity, and showed that this deficit increased with length of the item sequences to be remembered. However, this deficit was observed only in children with mild intellectual disability; the performance of children with borderline intellectual disability corresponded with that of a control group of 7-year-olds matched for mental age. The findings are discussed in the context of the two-component model of the phonological loop. They indicate that deficits in storage capacity are associated with deficits in language development and thus seem to be one of the causes of cognitive impairment in individuals with mild intellectual disability.     

小包装全氟丙烷气体动力学实验研究

为检验塑料小包装全氟丙烷气体（C3F8）在不同包装和储存方法时浓度变化，将装有5～7mlC3F8的聚氯乙烯小袋，根据不同储藏温度和外包装方法随机分成四组：（1）22℃聚乙烯外包装，（2）36℃聚乙烯外包装，（3）22℃铝箔真空外包装，（4）-29℃聚乙烯外包装；每一组C3F8小袋气体存放一定时间后，应用气相色谱分析方法进行浓度测量。结果：第3组C3F8浓度最高和稳定，第2组浓度随放置时间降低最明显，第4组是临床应用气体的储藏和包装方法，其30天样本浓度和第3组相等，但放置一年时浓度降低。结果显示：塑料小包装C3F8予以铝箔真空外包装是一种可行的方法，利于C3F8运输和普及；聚乙烯外包装的C3F8，应放在-29℃保存，时间不超过一年。